Betadex Sulfobutyl Ether Sodium Excipients in Posaconazole

Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 is a China DELI's new type of anionic high soluble cyclodextrin derivatives. Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 is a sodium salt produced when Betadex is alkylated by 1,4-butanesulfonic acid lactone under alkaline conditions. It is an anion, highly water-soluble Betadex derivative. It can be used as a solubilizer, wetting agent, chelating agent (complexing agent) and polyvatent masking agent.

Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 has been used in injection, oral, nasal and eye medicines. It has a special affinity and inclusion for nitrogen drugs. Increase the drug's stability, solubility, safety (Include drug molecules to form non-covalent). Reduce renal toxicity, ease drug hemolysis. Control the drug release rate, cover the bad smell. Our company produces Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 and Hydroxypropyl Βetadex CAS 128446-35-5 all can provide free samples

Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 Standards

[CAS NO]: 128410-00-0
[Molecular formula]: C₄₂H₇₀-nO₃₅•(C₄H₈SO₃Na)n
[Specification]: 500g/Bag; 1kg/Bag; 10kg/bag/drum; or as your requirement
[Category]: Pharmaceutical excipients
[Storage]: Seal preservation.

[Period of validity]: 36 months

1. Application in injection

Role: Solubilizer, stabilizer, improve the solubility and stability of insoluble drugs, so that insoluble drugs can be developed into injectables.

Examples: Sulfobutyl betacyclodextrin is used to improve the solubility of docetaxel, voriconazole, ibuprofen and indomethacin; sulfobutyl betacyclodextrin is used to improve the stability of carmustine.

2. Application in oral formulation

Role: Solubilizer, stabilizer, improve the bioavailability of insoluble drugs.

Example: Sulfobutyl betacyclodextrin is used to improve the bioavailability of flunarizine, danazol, hydrogenated prednisone and prasugrel.

3、Application in ophthalmic preparations

Role: Solubilizer, stabilizer, reduce drug irritation.

Example: Sulfobutyl betacyclodextrin is used to improve the irritation and stability of furfuracoum, dipivoxylin, baroxacin and ganciclovir.

4、Application in the nasal preparation

Effects: Increase the permeability of the nasal mucosa, improve the solubility and stability of the drug, and improve the metabolic rate of the drug at the target site of administration.

Example: Sulfobutyl betacyclodextrin is used to improve the solubility and stability of midazolam.

5、Ointment softener

Effects: Improve the solubility and stability of drugs.

Example: Sulfobutyl betacyclodextrin is used to improve the solubility and stability of nimesulide.