DELI is a professional China DELI Brand Hydroxypropyl Betadex CAS 128446-35-5 and DELI Brand Betadex Sulfobutyl Ether Sodium CAS 182410-00-0 manufacturers and suppliers. Now has an annual output of 500 tons of Hydroxypropyl Betadex CAS 128446-35-5.
Hydroxypropyl Βetadex CAS Oral Grade
[Product Name]: Hydroxypropyl Βetadex CAS 128446-35-5
[CAS NO]: 128446-35-5
[DMF]: DMF 034772[Period of validity]: 36 months
Hydroxypropyl beta cyclodextrin (HPBCD) injection grade is widely used in pharmaceutical applications due to its ability to enhance the solubility and stability of various drugs. Here are some key applications:
1. Solubilizing Agent**: HPBCD is used to increase the solubility of poorly water-soluble drugs, making them more bioavailable. This is particularly useful for intravenous and intramuscular injections where high solubility is crucial.
2. Stabilizing Agent**: HPBCD helps stabilize drugs that are prone to degradation. It forms inclusion complexes with drug molecules, protecting them from environmental factors such as light, heat, and oxidation.
3. Reducing Irritation**: HPBCD can reduce the irritation caused by some injectable drugs. By forming inclusion complexes, it can encapsulate irritating molecules, minimizing their contact with tissues.
4. Controlled Release**: HPBCD can be used in formulations to control the release rate of the active pharmaceutical ingredient, providing a more consistent therapeutic effect.
5. Compatibility with Biological Systems**: HPBCD is biocompatible and less toxic, making it suitable for use in injectable formulations.
6. Applications in Specific Drugs**: HPBCD is used in the formulation of various injectable drugs, such as itraconazole, docetaxel, and other lipophilic drugs that require enhanced solubility and stability for effective therapeutic action.
These applications make HPBCD injection grade a versatile and valuable excipient in the pharmaceutical industry, improving the efficacy and safety of injectable medications.